The six members of Laboria Cuboniks are brought together for the first time in a single volume that delves into their fundamental themes while also introducing us to their most recent work. Diann Bauer, Helen Hester, Patricia Reed, Amy Ireland, Katrina Burch, and Lucca Fraser shook the "accelerosphere" in 2015 with the creation of their famous manifesto, sparking global interest in xenofeminism. Since then, the prefix "xeno" has become an infectious agent that proliferates and recodes our relationship with alienation and the strange, freedom, collective thought, aesthetics, and sexuality. In the essays collected in this compilation, the group of brilliant philosophers and artists continues the work begun with Laboria Cuboniks, anticipating new challenges concerning human self-understanding, climate change, evolutionary computing, posthuman feminism, and postcybernetic politics, as well as our capacity to navigate an environment of interconnected scales and scenarios. Ours is a “world in vertigo”; and reality is often stranger than we imagine. Learning to recognize our own alienation will provide us with a unique opportunity to unleash the creative potential of the human species and its transformation.